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1

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

Nik-Zainal, Serena, Davies, Helen, Staaf, Johan, Ramakrishna, Manasa, Glodzik, Dominik, Zou, Xueqing, Martincorena, Inigo, Alexandrov, Ludmil B., Martin, Sancha, Wedge, David C., Van Loo, Peter, Ju, Y

Journal:

Year:

2016

Language:

english

File:

PDF, 5.72 MB

english, 2016

2

Universal Patterns of Selection in Cancer and Somatic Tissues

Martincorena, Iñigo, Raine, Keiran M., Gerstung, Moritz, Dawson, Kevin J., Haase, Kerstin, Van Loo, Peter, Davies, Helen, Stratton, Michael R., Campbell, Peter J.

Journal:

Year:

2018

Language:

english

File:

PDF, 108 KB

english, 2018

3

Evidence of non-random mutation rates suggests an evolutionary risk management strategy

Martincorena, Iñigo, Seshasayee, Aswin S. N., Luscombe, Nicholas M.

Journal:

Year:

2012

Language:

english

File:

PDF, 454 KB

english, 2012

4

Non-random mutation: The evolution of targeted hypermutation and hypomutation

Martincorena, Iñigo, Luscombe, Nicholas M.

Journal:

Year:

2013

Language:

english

File:

PDF, 286 KB

english, 2013

5

Direct Competition between hnRNP C and U2AF65 Protects the Transcriptome from the Exonization of Alu Elements

Zarnack, Kathi, König, Julian, Tajnik, Mojca, Martincorena, Iñigo, Eustermann, Sebastian, Stévant, Isabelle, Reyes, Alejandro, Anders, Simon, Luscombe, Nicholas M., Ule, Jernej

Journal:

Year:

2013

Language:

english

File:

PDF, 3.82 MB

english, 2013

6

Lexical access changes in patients with multiple sclerosis: A two-year follow-up study

Sepulcre, Jorge, Peraita, Herminia, Goñi, Joaquín, Arrondo, Gonzalo, Martincorena, Iñigo, Duque, Beatriz, Vélez de Mendizábal, Nieves, Masdeu, Joseph C., Villoslada, Pablo

Journal:

Journal of Clinical and Experimental Neuropsychology

Year:

2011

Language:

english

File:

PDF, 334 KB

english, 2011

7

The Organization of Local and Distant Functional Connectivity in the Human Brain

Sepulcre, Jorge, Liu, Hesheng, Talukdar, Tanveer, Martincorena, Iñigo, Yeo, B. T. Thomas, Buckner, Randy L., Sporns, Olaf

Journal:

PLoS Computational Biology

Year:

2010

Language:

english

File:

PDF, 6.62 MB

english, 2010

8

Mutational signatures associated with tobacco smoking in human cancer

Alexandrov, L. B., Ju, Y. S., Haase, K., Van Loo, P., Martincorena, I., Nik-Zainal, S., Totoki, Y., Fujimoto, A., Nakagawa, H., Shibata, T., Campbell, P. J., Vineis, P., Phillips, D. H., Stratton, M.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.23 MB

english, 2016

9

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

Ju, Young Seok, Martincorena, Inigo, Gerstung, Moritz, Petljak, Mia, Alexandrov, Ludmil B., Rahbari, Raheleh, Wedge, David C., Davies, Helen R., Ramakrishna, Manasa, Fullam, Anthony, Martin, Sancha, A

Journal:

Year:

2017

Language:

english

File:

PDF, 3.32 MB

english, 2017

10

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal

Mitchell, Thomas J., Turajlic, Samra, Rowan, Andrew, Nicol, David, Farmery, James H.R., O’Brien, Tim, Martincorena, Inigo, Tarpey, Patrick, Angelopoulos, Nicos, Yates, Lucy R., Butler, Adam P., Raine,

Journal:

Year:

2018

Language:

english

File:

PDF, 7.09 MB

english, 2018

11

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences

Nik-Zainal, Serena, Davies, Helen, Staaf, Johan, Ramakrishna, Manasa, Glodzik, Dominik, Zou, Xueqing, Martincorena, Inigo, Alexandrov, Ludmil B., Martin, Sancha, Wedge, David C., Van Loo, Peter, Ju, Y

Journal:

Year:

2019

Language:

english

File:

PDF, 337 KB

english, 2019

12

A 1.2 V Current-Mode RMS-to-DC Converter Based on a Novel Two-Quadrant Electronically Simulated MOS Translinear loop

Arraiza, Maite Martincorena, Blas, Carlos A. De La Cruz, Miguel, Jose Maria Algueta, Lopez-Martin, Antonio

Journal:

IEEE Transactions on Circuits and Systems II: Express Briefs

Year:

2019

Language:

english

File:

PDF, 2.16 MB

english, 2019

13

[IEEE 2020 IEEE International Symposium on Circuits and Systems (ISCAS) - Sevilla (2020.10.12-2020.10.14)] 2020 IEEE International Symposium on Circuits and Systems (ISCAS) - A 1.2 V Current-Mode RMS-to-DC Converter Based on a Novel Two-Quadrant Electronically Simulated MOS Translinear Loop

Martincorena-Arraiza, Maite, De La Cruz Blas, Carlos A., Algueta-Miguel, Jose Maria, Lopez-Martin, Antonio

Year:

2020

File:

PDF, 281 KB

2020

14

The semantic organization of the animal category: evidence from semantic verbal fluency and network theory

Joaquín Goñi, Gonzalo Arrondo, Jorge Sepulcre, Iñigo Martincorena, Nieves Vélez de Mendizábal, Bernat Corominas-Murtra, Bartolomé Bejarano, Sergio Ardanza-Trevijano, Herminia Peraita, Dennis P. Wall,

Journal:

Cognitive Processing

Year:

2011

Language:

english

File:

PDF, 727 KB

english, 2011

15

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia

Papaemmanuil, Elli, Rapado, Inmaculada, Li, Yilong, Potter, Nicola E, Wedge, David C, Tubio, Jose, Alexandrov, Ludmil B, Van Loo, Peter, Cooke, Susanna L, Marshall, John, Martincorena, Inigo, Hinton,

Journal:

Nature Genetics

Year:

2014

Language:

english

File:

PDF, 1.21 MB

english, 2014

16

Inactivating CUX1 mutations promote tumorigenesis

Wong, Chi C, Martincorena, Inigo, Rust, Alistair G, Rashid, Mamunur, Alifrangis, Constantine, Alexandrov, Ludmil B, Tiffen, Jessamy C, Kober, Christina, Green, Anthony R, Massie, Charles E, Nangalia,

Journal:

Nature Genetics

Year:

2013

Language:

english

File:

PDF, 923 KB

english, 2013

17

Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

Bolli, Niccolo, Avet-Loiseau, Hervé, Wedge, David C., Van Loo, Peter, Alexandrov, Ludmil B., Martincorena, Inigo, Dawson, Kevin J., Iorio, Francesco, Nik-Zainal, Serena, Bignell, Graham R., Hinton, Jo

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 1.36 MB

english, 2014

18

Transmissible Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage

Murchison, E. P., Wedge, D. C., Alexandrov, L. B., Fu, B., Martincorena, I., Ning, Z., Tubio, J. M. C., Werner, E. I., Allen, J., De Nardi, A. B., Donelan, E. M., Marino, G., Fassati, A., Campbell, P.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.83 MB

english, 2014

19

Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2

Nangalia, J., Massie, C.E., Baxter, E.J., Nice, F.L., Gundem, G., Wedge, D.C., Avezov, E., Li, J., Kollmann, K., Kent, D.G., Aziz, A., Godfrey, A.L., Hinton, J., Martincorena, I., Van Loo, P., Jones,

Journal:

New England Journal of Medicine

Year:

2013

Language:

english

File:

PDF, 921 KB

english, 2013

20

Recurrent PTPRB and PLCG1 mutations in angiosarcoma

Behjati, Sam, Tarpey, Patrick S, Sheldon, Helen, Martincorena, Inigo, Van Loo, Peter, Gundem, Gunes, Wedge, David C, Ramakrishna, Manasa, Cooke, Susanna L, Pillay, Nischalan, Vollan, Hans Kristian M,

Journal:

Nature Genetics

Year:

2014

Language:

english

File:

PDF, 456 KB

english, 2014

21

Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

Tubio, J. M. C., Li, Y., Ju, Y. S., Martincorena, I., Cooke, S. L., Tojo, M., Gundem, G., Pipinikas, C. P., Zamora, J., Raine, K., Menzies, A., Roman-Garcia, P., Fullam, A., Gerstung, M., Shlien, A.,

Journal:

Year:

2014

Language:

english

File:

PDF, 2.85 MB

english, 2014

22

Genome sequencing of normal cells reveals developmental lineages and mutational processes

Behjati, Sam, Huch, Meritxell, van Boxtel, Ruben, Karthaus, Wouter, Wedge, David C., Tamuri, Asif U., Martincorena, Iñigo, Petljak, Mia, Alexandrov, Ludmil B., Gundem, Gunes, Tarpey, Patrick S., Roeri

Journal:

Year:

2014

Language:

english

File:

PDF, 1.08 MB

english, 2014

23

Processed pseudogenes acquired somatically during cancer development

Cooke, Susanna L., Shlien, Adam, Marshall, John, Pipinikas, Christodoulos P., Martincorena, Inigo, Tubio, Jose M.C., Li, Yilong, Menzies, Andrew, Mudie, Laura, Ramakrishna, Manasa, Yates, Lucy, Davies

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 455 KB

english, 2014

24

SWITCHER-RANDOM-WALKS: A COGNITIVE-INSPIRED MECHANISM FOR NETWORK EXPLORATION

GOÑI, JOAQUÍN, MARTINCORENA, IÑIGO, COROMINAS-MURTRA, BERNAT, ARRONDO, GONZALO, ARDANZA-TREVIJANO, SERGIO, VILLOSLADA, PABLO

Journal:

International Journal of Bifurcation and Chaos

Year:

2010

Language:

english

File:

PDF, 1.39 MB

english, 2010

25

High burden and pervasive positive selection of somatic mutations in normal human skin

Martincorena, I., Roshan, A., Gerstung, M., Ellis, P., Van Loo, P., McLaren, S., Wedge, D. C., Fullam, A., Alexandrov, L. B., Tubio, J. M., Stebbings, L., Menzies, A., Widaa, S., Stratton, M. R., Jone

Journal:

Year:

2015

Language:

english

File:

PDF, 3.55 MB

english, 2015

26

Somatic mutation in cancer and normal cells

Martincorena, I., Campbell, P. J.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.80 MB

english, 2015

27

Constrained positive selection on cancer mutations in normal skin

Martincorena, Iñigo, Jones, Philip H., Campbell, Peter J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 514 KB

english, 2016

28

1804 The driver landscape of breast cancer metastasis and relapse

Yates, L., Knappskog, S., Martincorena, I., Gerstung, M., Stratton, M., Lonning, P.E., Campbell, P.

Journal:

European Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 58 KB

english, 2015

29

Tissue-specific mutation accumulation in human adult stem cells during life

Blokzijl, Francis, de Ligt, Joep, Jager, Myrthe, Sasselli, Valentina, Roerink, Sophie, Sasaki, Nobuo, Huch, Meritxell, Boymans, Sander, Kuijk, Ewart, Prins, Pjotr, Nijman, Isaac J., Martincorena, Inig

Journal:

Year:

2016

Language:

english

File:

PDF, 2.97 MB

english, 2016

30

Precision oncology for acute myeloid leukemia using a knowledge bank approach

Gerstung, Moritz, Papaemmanuil, Elli, Martincorena, Inigo, Bullinger, Lars, Gaidzik, Verena I, Paschka, Peter, Heuser, Michael, Thol, Felicitas, Bolli, Niccolo, Ganly, Peter, Ganser, Arnold, McDermott

Journal:

Nature Genetics

Year:

2017

Language:

english

File:

PDF, 2.03 MB

english, 2017

31

Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations

Brammeld, Jonathan S., Petljak, Mia, Martincorena, Inigo, Williams, Steven P., Alonso, Luz Garcia, Dalmases, Alba, Bellosillo, Beatriz, Robles-Espinoza, Carla Daniela, Price, Stacey, Barthorpe, Syd, T

Journal:

Genome Research

Year:

2017

Language:

english

File:

PDF, 1.15 MB

english, 2017

32

Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma

Behjati, Sam, Tarpey, Patrick S., Haase, Kerstin, Ye, Hongtao, Young, Matthew D., Alexandrov, Ludmil B., Farndon, Sarah J., Collord, Grace, Wedge, David C., Martincorena, Inigo, Cooke, Susanna L., Dav

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 2.00 MB

english, 2017

33

Genomic Evolution of Breast Cancer Metastasis and Relapse

Yates, Lucy R., Knappskog, Stian, Wedge, David, Farmery, James H.R., Gonzalez, Santiago, Martincorena, Inigo, Alexandrov, Ludmil B., Van Loo, Peter, Haugland, Hans Kristian, Lilleng, Peer Kaare, Gunde

Journal:

Year:

2017

Language:

english

File:

PDF, 4.95 MB

english, 2017

34

The driver landscape of sporadic chordoma

Tarpey, Patrick S., Behjati, Sam, Young, Matthew D., Martincorena, Inigo, Alexandrov, Ludmil B., Farndon, Sarah J., Guzzo, Charlotte, Hardy, Claire, Latimer, Calli, Butler, Adam P., Teague, Jon W., Sh

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 938 KB

english, 2017

35

Universal Patterns of Selection in Cancer and Somatic Tissues

Martincorena, Iñigo, Raine, Keiran M., Gerstung, Moritz, Dawson, Kevin J., Haase, Kerstin, Van Loo, Peter, Davies, Helen, Stratton, Michael R., Campbell, Peter J.

Journal:

Year:

2017

Language:

english

File:

PDF, 3.43 MB

english, 2017

36

Barcoding of human haematopoietic stem and progenitor cells by whole genome sequencing reveals clonal dynamics of haematopoiesis

Lee-Six, Henry, Friesgaard-Oebro, Nina, Shepherd, Mairi, Grossmann, Sebastian, Dawson, Kevin, Belmonte, Miriam, Osborne, Robert, Martincorena, Inigo, Arias, Carlos Gonzalez, Grinfeld, Jacob, Laurenti,

Journal:

Experimental Hematology

Year:

2017

Language:

english

File:

PDF, 220 KB

english, 2017

37

Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines

Maura, F, Petljak, M, Lionetti, M, Cifola, I, Liang, W, Pinatel, E, Alexandrov, L, Fullam, A, Martincorena, I, Dawson, K J, Angelopoulos, N, Samur, M K, Szalat, R, Zamora, J, Tarpey, P, Davies, H, Cor

Journal:

Year:

2017

Language:

english

File:

PDF, 1024 KB

english, 2017

38

Recurrent histone mutations in T-cell acute lymphoblastic leukaemia

Collord, Grace, Martincorena, Inigo, Young, Matthew D., Foroni, Letizia, Bolli, Niccolo, Stratton, Michael R., Vassiliou, George S., Campbell, Peter J., Behjati, Sam

Journal:

British Journal of Haematology

Year:

2018

Language:

english

File:

PDF, 203 KB

english, 2018

39

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

Wedge, David C., Gundem, Gunes, Mitchell, Thomas, Woodcock, Dan J., Martincorena, Inigo, Ghori, Mohammed, Zamora, Jorge, Butler, Adam, Whitaker, Hayley, Kote-Jarai, Zsofia, Alexandrov, Ludmil B., Van

Journal:

Nature Genetics

Year:

2018

Language:

english

File:

PDF, 2.04 MB

english, 2018

40

Pathway-based dissection of the genomic heterogeneity of cancer hallmarks’ acquisition with SLAPenrich

Iorio, Francesco, Garcia-Alonso, Luz, Brammeld, Jonathan S., Martincorena, Iňigo, Wille, David R., McDermott, Ultan, Saez-Rodriguez, Julio

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 5.63 MB

english, 2018

41

Cancer-mutation network and the number and specificity of driver mutations

Iranzo, Jaime, Martincorena, Iñigo, Koonin, Eugene V.

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.60 MB

english, 2018

42

GOTHiC, a probabilistic model to resolve complex biases and to identify real interactions in Hi-C data

Mifsud, Borbala, Martincorena, Inigo, Darbo, Elodie, Sugar, Robert, Schoenfelder, Stefan, Fraser, Peter, Luscombe, Nicholas M., Isalan, Mark

Journal:

Year:

2017

Language:

english

File:

PDF, 2.39 MB

english, 2017

43

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

Ju, Young Seok, Alexandrov, Ludmil B, Gerstung, Moritz, Martincorena, Inigo, Nik-Zainal, Serena, Ramakrishna, Manasa, Davies, Helen R, Papaemmanuil, Elli, Gundem, Gunes, Shlien, Adam, Bolli, Niccolo,

Journal:

Year:

2014

Language:

english

File:

PDF, 1.74 MB

english, 2014

44

Genomic patterns of progression in smoldering multiple myeloma

Bolli, Niccolò, Maura, Francesco, Minvielle, Stephane, Gloznik, Dominik, Szalat, Raphael, Fullam, Anthony, Martincorena, Inigo, Dawson, Kevin J., Samur, Mehmet Kemal, Zamora, Jorge, Tarpey, Patrick, D

Journal:

Nature Communications

Year:

2018

File:

PDF, 1.72 MB

2018

45

Genomic patterns of progression in smoldering multiple myeloma

Bolli, Niccolò, Maura, Francesco, Minvielle, Stephane, Gloznik, Dominik, Szalat, Raphael, Fullam, Anthony, Martincorena, Inigo, Dawson, Kevin J., Samur, Mehmet Kemal, Zamora, Jorge, Tarpey, Patrick, D

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 1.72 MB

english, 2018

46

Population dynamics of normal human blood inferred from somatic mutations

Lee-Six, Henry, Øbro, Nina Friesgaard, Shepherd, Mairi S., Grossmann, Sebastian, Dawson, Kevin, Belmonte, Miriam, Osborne, Robert J., Huntly, Brian J. P., Martincorena, Inigo, Anderson, Elizabeth, O’N

Journal:

Year:

2018

Language:

english

File:

PDF, 5.56 MB

english, 2018

47

An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures

Collord, Grace, Tarpey, Patrick, Kurbatova, Natalja, Martincorena, Inigo, Moran, Sebastian, Castro, Manuel, Nagy, Tibor, Bignell, Graham, Maura, Francesco, Young, Matthew D., Berna, Jorge, Tubio, Jose

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 2.64 MB

english, 2018

48

Neutral tumor evolution?

Tarabichi, Maxime, Martincorena, Iñigo, Gerstung, Moritz, Leroi, Armand M., Markowetz, Florian, Spellman, Paul T., Morris, Quaid D., Lingjærde, Ole Christian, Wedge, David C., Van Loo, Peter

Journal:

Nature Genetics

Year:

2018

Language:

english

File:

PDF, 1.89 MB

english, 2018

49

Somatic mutation and clonal expansions in human tissues

Martincorena, Inigo

Journal:

Genome Medicine

Year:

2019

Language:

english

File:

PDF, 1.11 MB

english, 2019

50

Genomic landscape and chronological reconstruction of driver events in multiple myeloma

Maura, Francesco, Bolli, Niccoló, Angelopoulos, Nicos, Dawson, Kevin J., Leongamornlert, Daniel, Martincorena, Inigo, Mitchell, Thomas J., Fullam, Anthony, Gonzalez, Santiago, Szalat, Raphael, Abascal

Journal:

Nature Communications

Year:

2019

Language:

english

File:

PDF, 2.10 MB

english, 2019

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